HTM One is a unifying framework designed to simplify and strengthen HTM by aligning one inventory, one program, and one budget into a single operational model. This session explores how fragmentation across these domains creates avoidable risk, inefficiency, and financial distortion within healthcare organizations. Attendees will review real-world examples demonstrating how HTM One improves data accuracy, regulatory defensibility, and leadership communication. The presentation also provides a practical roadmap and actionable strategies for implementing the framework to improve alignment, accountability, and overall HTM performance.